CADASIL is an abbreviation of Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (OMIM# 125310). It represents the paradigm of genetic cerebral microvascular diseases. The cardinal clinical feature is recurrent ischemic strokes since the early stages ...
Autoimmune diseases are widely increasing nowadays due to many factors like lifestyles, genetic disorders, and environmental factors. Many research studies were done to identify the relation between blood grouping with positive or negative rhesus factors and autoimmune diseases ...
The Epstein-Barr Virus (EBV) is a DNA (deoxyribonucleic acid) virus, whose only known host is man [1]. Primary EBV infection usually manifests as asymptomatically, indistinguishable from other viral infections, or as "Infectious Mononucleosis" (IMN) [2-7]. IMN is clinically characterized ...
The biological roles of naturally occurring Deuterium (D), heavy isotope of hydrogen, especially in cell growth, have been described more and more precisely since the first reports in the early 90's [1]. Today, D is known to play a determinative role in cell cycle regulation, gene expression, and cancer ...
Fetal Umbilical Vein Varix (FUVV) is a rare malformation of the umbilical cord. In most cases the varix is located intra abdominally arising between its entry into the abdomen and the portal system (fetal intra-abdominal umbilical vein varix FIUVV). ...
Materia Medica described by Dioscorides indicates that saffron is the fresher the better, and is used for poor circulation and uterine medicine, for bowel movements and as a tonic. In Greek time it was used as an aphrodisiac. Saffron was brought to China via India around the 13th century and ...
The term "apoplexy" was used in the ancient Greco-Roman era to describe a condition in which the patient "suddenly falls with abrupt abolition of all activities of the mind while retaining pulse and respiration " [1]. The term "stroke" to symbolize apoplexy was first used by Mr. William Cole ...
Iron deficiency anaemia (IDA) is an under recognised risk factor for acute ischaemic stroke [1]. In an observational study conducted in Pakistan, it was identified that 10.42% of the patients diagnosed with acute ischaemic stroke had IDA [2]. Scherbakov et al. (2022) identified that iron deficiency ...
Merkel Cell Carcinoma (MCC) is a rare and aggressive neuroendocrine skin cancer characterized by high risk of recurrence and poor prognosis at an advanced stage [1]. ...
Uncommon but possibly fatal, spontaneous haemopneumothorax needs to be identified an treated right away. It is mostly seen in 3% of patients with spontaneous pneumothorax [1] and is characterised by air and blood in the pleural space, which can lead to breathing difficulties ...
Antiphospholipid syndrome (APS) is a chronic systemic autoimmune disease characterized by vascular thrombosis and pathological course of pregnancy with elevated levels of antiphospholipid antibodies (aPL). The chronic course and multisystemic involvement, as well as the need ...
Eagle's syndrome is a set of clinical symptoms caused by an elongated styloid process or a calcified stylohyoid ligament, first described and named after American otolaryngologist Watt Weems Eagle (1898–1980) in 1937. Interestingly, the pathoetiology of the syndrome remains unclear ...
Colorectal cancer is the third most common cancer in the world [1]. Approximatively, 15-30% of patients present synchronous liver metastasis, while 20-50% of patients will develop metachronous disease, with a most common location in the liver [2]. Considering that the R0 resection of colorectal ...
Malaria is a significant public health issue and a leading cause of death in developing countries and tropical regions [1]. According to the World Health Organisation (WHO), an estimated 3.2 billion people in 95 countries and territories are at risk of contracting malaria and developing the disease ...
Lung cancer (LC) remains the worldwide leading cause of death from all types of cancer. Unfortunately, approximately 75% of patients are diagnosed at an advanced stage of the disease (III, IV) [1]. Despite significant investment and advancement in LC research, only 16% of LCs are detected ...
Esophageal atresia (EA) and hypertrophic pyloric stenosis (HPS) are rare congenital anomalies that individually require surgical interventions. However, the simultaneous occurrence of these conditions has only been reported in a few cases. Kate et al. [1] presented a case report describing ...
Myasthenia gravis (MG) is a rare autoimmune disorder of the neuromuscular junction associated with post-synaptic skeletal muscle membrane protein autoantibodies, most commonly (80%) against the nicotinic acetylcholine receptors (ACh-R) [1]. Other antibodies against muscle-specific ...
Cell separation is a powerful tool enabling the isolation of cellular subpopulations for biological research and clinical applications [1-5]. Many cell separation techniques are currently commercially available, which are predominantly based on three methodologies: adherence, density, and cell ...
A ketogenic diet can exert neuroprotection in epilepsy by reducing seizure frequencies [1]. Clinical studies also suggest that ketone metabolism may improve cognitive function in other neurological conditions such as Alzheimer's [2,3] and Parkinson's Disease [4]. There are no published ...
Since abnormal lipid metabolism-related to H Hypobetalipoproteinemia (HBL) is associated with a high risk of atherosclerotic vascular diseases such as cerebrovascular diseases and coronary artery diseases, academic societies and medical associations have established guidelines ...
Peer review is an essential process in any publications refereeing a mutual process that allows evaluating manuscripts submitted to a journal and commented upon by independent research experts within the similar field of research...
Open Access is the free of charge, instant, online availability of research articles, together with the rights to use these articles fully in the digital milieu. It provides unrestricted use and reuse...
Plagiarism is a part of Journalistic ethic where it is considered to be a crime. The act of taking content, writing, statement or an idea that is already published is known as plagiarism. Whenever you consider using any paraphrase, sum up, or take terms, phrases, sentences or statements...