Acquired A haemophilia (AHA) is very rare autoimmune disease (incidence 1 person per million/year) caused by the production of anti VIII factor (FVIII) autoantibodies. It is mostly idiopathic, but it can be associated with elderly, pregnancy or neoplastic, infectious or autoimmune diseases. The diagnosis is confirmed by isolate prolongation of aPTT time, reduced levels of FVIII and the detection ...
V. furnissii is a gram-negative, straight/slightly curved rod that is motile via polar flagella [1]. V. furnissii has frequently been isolated from the estuarine environment [2]. It is one of the 11 non-cholera Vibrio species pathogenic in humans that cause clinical infections such as diarrhea, bacteremia, and cellulitis [2-5]. The bacterium resembles Aeromonas hydrophila in phenotypical and biochemical ...
Anaemia is one of the most common blood disorders, affecting about one third of the world population [1]. Chronic, occult blood loss is one of the most common etiologies of anaemia, leading to iron deficiency (ID) anaemia [2]. Chronic Heart Failure (CHF) is the end stage of multiple cardiac disorders, ...
Meningiomas originate from the meningeal covering of the central nervous system and are the most common primary tumor of the central nervous system with an annual incidence of about 5 per 100,000 people. Meningiomas are usually benign and rarely have malignant manifestations [1,2]. ...
Cutaneous angiosarcoma is a rare and aggressive form of cancer that affects the blood vessels and lymph vessels of the skin and soft tissues. It is estimated to account for only 2% of all skin malignancies, and its incidence can vary depending on the location and organ affected. It commonly affects the head and neck region, specifically the scalp, face and neck [1]. The malignant cells of angiosarcoma form ...
Idiopathic Orbital Inflammatory Syndrome (IOIS) is an inflammatory syndrome of unknown aetiology, also known as orbital pseudotumour. It is a non-infective inflammatory condition which can affect all the anatomical structures that make up the orbit and may also extend to involve periorbital sites [1,2]. It is a rare finding in children and can have a highly variable clinical presentation ranging from ...
Suicidal ideation is a multifaceted and complex psychopathological symptom changing in intensity and duration. In schizophrenic patients, the lifetime prevalence of suicidal ideation was 34,5%; in comparison, point prevalence was 29,9% [1]. However, a clear suicide plan was observed between 6,4% and 13% of patients [1] and fortunately, only a tiny part of them pass suicidal intention and engage ...
Intrahepatic Cholestasis of Pregnancy (ICP) is a liver disorder characterized by maternal pruritus, raised serum bile acids, elevated liver enzymes and adverse fetal outcomes, mostly occurs at the end of the second trimester or in the third trimester of pregnancy. It is most common in South America, particularly in Chile, where reports the incidence of 10% early [1], and as high as 6% in Chongqing, ...
Dengue fever presenting as acute hypokalemic quadriparesis is uncommon finding, however neurological manifestations of dengue fever are increasingly being recognized over the last decade. The neurological complications of dengue are rare with incidence ranging from 0.5% to 21% [1]. More common neurological presentations are meningitis and encephalitis. Guillain-Barre Syndrome ...
Melanoma is a malignant cutaneous tumor that accounts for nearly 2% of cancer deaths worldwide. Acral melanoma is a rare melanoma subtype occurring on the palms, soles, and nail units, and nodular melanomas are characterized by prominent vertical invasion [1,2]. Although the role that trauma plays in the pathogenesis of melanoma is controversial, studies have demonstrated an association between ...
Cardiovascular syphilis usually occurs 10-20 years after the initial syphilis infection [1]. Syphilitic aortitis classically involves aortic root, resulting in Coronary Ostial Stenosis (COS) and aortic valve insufficiency [2]. COS is the second most common complication of syphilitic aortitis [3], and is caused by aortic wall thickening, and is characterized with normal coronary distal ...
Jeune syndrome, also known as asphyxiating thoracic dystrophy, was first described by Jeune et al in a couple of siblings back in 1955. He described 2 boys with certain distinctive characteristics, particularly a severely narrow thorax [1]. We now know it is a rare genetic condition presented in only 1 per 1000 000 -130 000 live births in the USA [1]. Because of the lack of reported data, actual incidence ...
We present the case of a 52-year-old lady with Marfan syndrome, permanent pacemaker, Mitral Valve (MV) repair at the age of 34 years old and mitral valve replacement with a mechanical bileaflet prosthesis at the age of 40 yo who was referred to our Emergency Department (ED) for exertional dyspnea. Approximately 2 months prior due to exhibition fatigue and shortness of breath she was advised to undergo ...
About half of the cells in the human brain are glial cells. Glial cell is a collective term for cells in nervous tissue that can be structurally and functionally distinguished from nerve cells (neurons) [1,2]. The discoverer of glial cells was Rudolf Virchow in the middle of the 19th century [3]. He assumed a supporting and holding function and therefore gave the cells the name glial cells, derived from the ...
Angiolipomas are a form of lipoma that are characterized by all features of a typical lipoma and may contain a vascular component. These benign growths typically form subcutaneously in the extremities, trunk, neck, and head and include those that form internally on the visceral walls of the torso, and in or near certain organs, such as the kidneys [1]. There are two kinds of angiolipomas ...
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