Over all Esophageal cancer is on the rise being the 8th most common cancer worldwide and 6th most common cause of death from cancer. It is, in particular, on the increase in the Sub-Saharan Africa and it is exclusively higher in the Eastern and Southern African Sub-regions [1]. It is also the leading diagnosis of elective admission for surgery performed at our University hospital [2]. Esophageal ...
Rat Bite Fever (RBF) is a zoonosis mainly caused by Streptobacillus moniliformis, a fastidious Gram-negative filamentous rod [1] transmitted by rodent bites or exposure to their fluids [2]. Symptoms such as fever, rash, and migratory polyarthralgia are commonly described [2] and complications may include endocarditis, meningitis, and focal abscesses [3]. Although the infection has a higher incidence ...
Stroke is the leading cause of disability and the second highest cause of human death [1]. Type 2 diabetes (T2D) is a kind of common metabolic disease; researches have already proven that T2D is an independent risk factor for stroke [2]. T2D can cause vascular endothelial dysfunction, increased early-age arterial stiffness, systemic inflammation and thickening of the capillary basal membrane ...
Diabetes Mellitus (DM) is one of the most serious health problems in the world [1,2]. Of the various diagnosis factors for DM, Fasting Blood Glucose (FBG) level is an important factor for diagnosis of prediabetes as it has a high association with the development rate of diabetes [3]. In addition, more recent studies have observed that prediabetes status is associated with risk of coronary heart disease ...
Clostridioides (formerly Clostridium) difficile infection (CDI) is a common nosocomial infection, with an estimated incidence of 73 per 100,000 patients residing in hospitals or health-care facilities [1]. It is generally related to prolonged antibiotic therapy, with subsequent disruption of the intestinal microbiome and selection of resistant and more virulent strains of the germ. ...
Pulmonary Sarcomatoid Carcinoma (PSC) is a rare NSCLC subtype characterized by poorly differentiated tumors containing sarcoma or sarcoma-like elements, rapid tumor growth, high level of blood-vessel invasion, and epithelial-to-mesenchymal transition, which worse prognosis is well known [1]. Except MET exon 14 alterations and other oncogene mutations, PSC commonly harbored high tumor ...
Total Knee Replacement (TKR) was the definitive methods for severe knee osteoarthritis, which postoperative complications such as pain, infection, thrombosis and nerve injury were relatively common, while ipsilateral femoral neck fracture was rare. We reported 2 cases in this paper whose ipsilateral femoral necks were fractured after TKR. The causality was considered of relating to changes ...
Tumour markers provide insight into the course of disease, response to therapy, and prognosis of patients with pancreatic adenocarcinoma, allowing physicians to determine marker level changes during disease. CA 19-9 (carbohydrate antigen sialyl Lewis A) is currently the only tumor marker approved by the United States Food and Drug Administration [1] for pancreatic cancer and is also ...
Ricin is considered one of the most potent toxins worldwide. It is obtained from the seeds of the castor oil plant, Ricinus communis. Ricin intoxication in humans and animals has been described since 100 years or more [1]. Nevertheless, symptomatic ricin intoxication is rare and has been described previously in scientific case reports [2,3]. Recently, a review was published which described ...
Isolated occult medial meniscus capsule separation (IOMMCS) is a subtype of meniscus injury, comprising the separation of the outermost part of the meniscus from the joint capsule junction due to its rich blood supply and good healing ability [1-3]. Its clinical symptoms are not typical, and the pain is evident after intense activity or when the activity amount is significant, while the MRI results ...
Thyroid storm is a potentially life-threatening endocrinologic emergency characterized by an exacerbation of a hyperthyroid state. Thyroid storm mortality rates are in the range of 8%- 25% despite modern advancements in its treatment and supportive measures. Hence prompt recognization is needed to initiate aggressive therapy. It can also cause diagnostic confusion after trauma as both ...
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a disease characterized by profound fatigue, cognitive dysfunction, sleep abnormalities, autonomic manifestations, pain, and other symptoms that are made worse by an exertion of any sort [1-3]. The global prevalence of ME/CFS ranges between 0.4 and 2.5% and it predominantly affects young adults between the ages of 20 to 40 years, ...
The relevance lies in the fact that attacks of trigeminal neuralgia are characterized by a severe course and the lack of sufficiently effective methods of treatment at home. Trigeminal Neuralgia (TN) is a chronic relapsing disease that occurs with remissions and exacerbations and is characterized by bouts of intense excruciating pain localized in the region of one or more branches of the trigeminal nerve. ...
Orthopaedic trauma is defined as a severe injury to part of the musculoskeletal system such as bones, joints, or ligaments [1]. Road traffic accidents is most common reason of Orthopaedic trauma, other reasons which can attribute to such trauma are industrial injuries, accidents fall and slip [2,3,]. Globally an estimated 103 million people died due to Road traffic accident and around 78.2 million ...
In many medical scientific and technical activities, Three-Dimensional (3D) organ models need to be reconstructed from serial two-dimensional (2D) medical slices, which is helpful for comprehending the structure of the organ and facilitating its automatic manipulation and analysis [1,2]. In recent years, 3D reconstruction of medical images has been widely used in medical ...
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