The presence of large perianal ulcers is not such a usual manifestation even in patients with pre-existing Crohn's Disease (CD) [1,2]. Differential diagnosis can be challenging, including infectious etiology, autoimmune, systematic diseases, cancer and less often medications [3]. ...
Normal occlusion is one that allows masticatory efficiency without changes in functions, considered by the correct position of the teeth in the dental arch, while malocclusions are considered as deviations of the teeth, jaws and dental arches, which can cause psychosocial problems, troubles with oral functions and greater susceptibility to trauma and dental disease problems in the affected individuals [1]. As a result of the interaction of hereditary, genetic or environmental factors [2]. ...
Cervical facet (also known as zygapophysial or zygapophyseal) joints have been concerned as the major origin of chronic posterior neck pain in approximately 26-70% cases [1,2]. Studies reported that chronic neck pain is mainly caused by C2-3 and/or C5-6 joint lesions [3], while pain in the C3 to C5 segments is affected by radiation referred pain [4,5]. Therapeutic benefit for facet joint pain has been reported with three types of interventions [6], including intraarticular ...
Patients with relapsed peripheral T-cell lymphoma carry a well-known poor prognosis. In the absence of transplant, reported median overall survival is estimated to be approximately 6 months [1]. Although prospective trials are lacking, a systematic review suggests a benefit to a salvage therapy followed by ASCT, with a pooled 1-to-5-year OS of 47% in the relapsed /refractory setting [2]. This treatment approach has been incorporated in expert consensus and major ...
Periprosthetic Joint Infections (PJIs) are difficult to treat and require medico-surgical management according to multidisciplinary setting. Suppressive Antibiotic Treatment (SAT) can be used when the infected implants cannot be exchanged or removed and when the conditions for optimal debridement with antibiotics and implant retention are not fulfilled. ...
Encephalocele is a rare birth defect of the neural tube in which there is a sac like protrusion or projection of brain and the meninges. It occurs when the neural tube, a narrow channel that allows the brain and spinal cord to develop, does not close completely during pregnancy. The portion of the brain that sticks outside the skull is usually covered by skin or thin membrane ...
Crouzon Syndrome (CS) is one of the most common craniosynostosis syndromes characterized by premature fusion and ossification of the cartilage of cranial sutures. CS is a rare autosomal dominant disorder (1 in 60000 live births) with complete penetrance and variable expressivity. This syndrome is responsible for several congenital anomalies such as craniofacial malformations, proptosis due to shallow orbits, ocular strabismus, hearing loss, maxillary hypoplasia ...
The patient was a 63-year-old male. He was admitted to the hospital after five days of fever. In May 2018, he underwent mitral valve and aortic valve replacement with left atrial appendage ligation in our hospital for rheumatic heart disease. The patient began to experience nasal congestion and rhinorrhea on April 7, 2019 and developed a fever (temperature not measured) accompanied ...
The mortality related to gastrointestinal bleeding ranges from 10–30%, so timely diagnosis and treatment are critical [1]. Approximately 5% of gastrointestinal bleeding lesions are between the proximal jejunum and terminal ileum [2]. These lesions are seldom seen in radiologic or endoscopic studies due to the length and peristalsis of the small intestine and overlapping loops [2]. ...
Individuals with diseases and injuries of the high spinal cord can experience complete paralysis below the neck, and even become ventilator-dependent, resulting in an inability to use their voice to communicate [17,19]. Until recently, such dramatic physical limitations also led to limitations in one's ability to take advantage of otherwise intact cognitive functions to pursue activities such as higher education or pursuing a profession [10,15,18]. However, with the advent ...
Testicular tumor is a common disease in urological department. Germ cell tumor is reported gaining a higher incidence in child and adolescent, while lymphoma represents in most cases in people with age > 60-year-old [1]. Histologically, the most common subtype of testicular lymphoma is diffuse large B-cell lymphoma (DLBCL), representing 80-90% of diagnosed tumors.
MKWS was first described in 1954 and is rare condition characterized by secretory diarrhoea and severe electrolyte depletion due to a villous adenoma [1]. It is characterised by secretory diarrhoea, dehydration, pre-renal acute kidney injury, and electrolyte abnormalities secondary to a hyper-secretory villous adenoma [2].
Worldwide, childhood diabetes is a public health problem. The 2019 report from the International Diabetes Federation estimated the annual growth of cases at around 3% with a greater incidence especially in Finland and Sweden [1]. Diabetes has social implications for children, their families and society, poorly documented, especially among young people.
Brucellosis is a bacterial disease that has been affecting humans and livestock for centuries, with over 500,000 new cases reported annually worldwide. The disease is caused by contact with infected animals, consumption of contaminated animal products, or inhaling airborne agents, and is a major public health hazard due to the increase of animal industries and urbanization [1].
MJH is an 18-years-old Chinese male. He had a wholesome childhood and has no mental illness. Computer games were his favorite. He has no family history of genetic disorders either. 3 years ago, he began to have hyposthenia of left upper limb. The manifestation was that he gradually had difficulty extending his left thumb. Dorsal flexion of the fingers was also problematic.
Small fiber neuropathy (SFN) has been recognized as a distinct disorder that selectively or predominantly affects thinly myelinated Aδ-fibers and unmyelinated C-fibers. Common symptoms include neuropathic pain (burning, electric shock-like sensation, pins and needles), decreased sensation to temperature and pinprick and autonomic disturbances.
Infectious disease outbreaks have recently had a substantial influence on the lives of millions of people [1,2]. At the end of 2019, just before the most fantastic Chinese festival, one such viral disease occurred in China [3]. It has been declared as COVID-19 disease and believed that the origin of COVID-19 was a shellfish retail market in Hunan that also offers a variety of wild animals, such as snakes, birds, bats, rabbits, and frogs.
Mortality of patients with Peptic Ulcer Bleeding (PUB) and other Upper Gastrointestinal Bleeding (UGIB) in a background of liver cirrhosis is seen in clinical practice and the literature [1-4]. In cirrhotic patients, UGIB is the deadliest complication [3]. Fifteen percent (15%) of these cirrhotic patients die within 6 weeks of symptoms [5].
Post-Cardiac Injury Syndrome (PCIS) constitutes a clinical syndrome of acute pericarditis due to injury to the pericardium [1]. The responsible pathophysiological mechanism is not completely elucidated. Possibly, a local and systemic inflammatory response of the pericardium sets in which clinically translates into pericardial chest pain, and/or fever, diffuse ST-segment elevation on ECG, pericardial friction rubs or pericardial effusion [2].
Venous thromboembolic events are among the most fatal complications of bariatric procedures and require attentive prophylaxis. Anti-embolic stockings, sequential pneumatic compression devices, early mobilization, and pharmacologic prophylaxis with Low Molecular Weight Heparins (LMWH) are the most common practices.
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