During the new era of treatment possibilities, Pancreatic Cancer (PC) is still a challenge for clinicians all over the world. Most cases are diagnosed in an advanced stage when only symptomatic surgery or palliative chemotherapy can prolong survival and reduce symptoms. Due to late diagnostics and increasing risk factors of modern society which are smoking, obesity, alcohol consumption and ...
A fifty-nine-year-old female presented with palpitations. She denied chest pain, shortness of breath or any other associated symptoms. She had a background of breast fibroadenoma and hypercholesterolemia, being an ex-smoker but with excellent exercise tolerance. ...
Pituitary apoplexy is a heterogeneous but rare clinical syndrome usually caused by hemorrhage into a pituitary adenoma or acute ischemia of a large macroadenoma [1]. Rarely, sphenoid sinus mucoceles may present with isolated cranial nerve palsies and mimic cavernous sinus or optic nerve compressive pathology [2-4]. However, the chronicity of these presentations can range from acute to more ...
We discuss the challenging case of a 77-year-old woman with long QT syndrome, in whom a permanent pacemaker implantation was initiated. The procedure was started by performing a skin incision on the left upper chest, followed by vascular cannulation into the left subclavian vein. When the pacemaker lead was indwelled, the patient experienced severe chest pain. Echocardiography revealed pericardial effusion; hence, we had to abort the pacemaker implantation and perform drainage. ...
Cancer, anorexia and alcoholism are diseases often associated whit a prolonged reduced caloric intake. The body adapts to the semi starvation by reduced insulin secretion and changes in the glucose metabolism. At the sudden resumption of adequate food intake, the increase insulin secretion and the cellular uptake of glucose, phosphate and potassium will increased. This may lead to a decrease ...
Vitamin B12 deficiency is a relatively common condition. Several etiologies exist such as inadequate uptake, pernicious anemia (loss of intrinsic factor secondary to atrophic gastritis), and decreased iliac absorption. Dietary vitamin B12 deficiency and pernicious anemia are considered the most common causes of severe vitamin B12 deficiency in children and adults, respectively [1]. Symptoms ...
Diabetes mellitus is a disorder of sugar metabolism, which has become one of the main diseases endangering human health. Due to the special pathological characteristics of diabetes (microcirculation disturbance and immune damage etc.). Compared with other people, these patients have a greater risk of renal damage and foot ulcer or gangrene [1]. Immunity levels ...
Immunosuppression is a double edged sword and has a risk of causing fatal opportunistic infections in high risk patients. Pulmonary mucormycosis is less common than the more prevalent rhino-cerebral-orbital form, but is more lethal as it involves vital structures for which one may not be able to perform radical surgery. ...
According to 2020 statistics, over 1 million new cases of gastric cancer and about 769,000 deaths were recorded worldwide, ranking 5th in the incidence rate and 4th in the death rate among malignant tumors [1]. The incidence of gastric cancer is related to H. pylori infection and environmental factors, etc. Flow survey data showed that the incidence of gastric cancer varies significantly across ...
Case 1, In the early July of this year, a 4-year-old girl came to our department for «itchy eyes for 2 months». Eye examination: A large number of brown crust-like attachments can be seen on the eyelid margin, and a large number of transparent eggs adhering and crawling brown worms under the slit lamp (Figure 1A, a, B, b), mild conjunctival hyperemia, remaining anterior segment (-). Intensive brown ...
Pigmented villonodular synovitis (PVNS) is defined as a rare, benign disease of the synovial tissue characterized by synovial hyperplasia, pigment deposition (hemosiderin), and swelling inside the affected joints, tendon sheaths, and bursae. The prevalence of PVNS estimated at 1.8 patients per million [1]. ...
Brain abscesses can have varied etiologies based on the possible sources of infection. Every attempt to find the organism is needed as empirical therapy is unlikely to be successful. This is a case report of one such patient, for whom the possible source of temporal lobe brain abscess was thought to be otogenic, based on which empirical therapy was given. As it was difficult to obtain brain tissue, ...
Non-small cell lung cancer (NSCLC) makes up approximately 85% of lung cancer cases. Among these, rearrangement in Anaplastic lymphoma kinase (ALK), which results in dysregulation and incorrect signaling through the ALK kinase domain [1] occurs in 3%−5% of NSCLC patients [2,3]. The advent of ALK tyrosine kinase inhibitors (TKIs) therapy has dramatically improved survival times for patients with stage IV ALK+ NSCLC, with a median overall survival (OS) rate of up to 7.5 years reported ...
Pineal region tumors are a heterogeneous group of lesions that includes several histological varieties: Tumor types occurring in the pineal region may or may not involve the pineal gland. Tumors that may occur in this region but are not necessarily pineal tumors include: germinoma, non-germinoma (eg, teratoma, endodermal sinus tumor, embryonal cell tumor, choriocarcinoma, and mixed tumors), meningioma, astrocytoma, ganglioglioma, and dermoid cysts. True pineal cell tumors-pineocytoma ...
GBS is an acquired acute polyradiculoneuropathy with typically characterized by ascending weakness and areflexia which is often preceded with common infections. It occasionally involves the oculomotor nerves but rarely involves the pupils. Here we reported a case of GBS who presented with bilateral tonic pupils associated with autonomic dysfunction and symmetrical weakness of the extremities. His serum GM1a was positive. This showed the association of the bilateral tonic pupils in a case ...
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